LAB 14: THE EFFECTIVENESS OF ANTACIDS. Jacqueline.The purpose of the experiment was to determine the relative basicity of Tums, Rolaids, Walgreens Tablet and Walgreens Antacid Liquid.An acid base titration was used to determine the amount of HCl needed to titrate one serving of each antacid product.Using the average of two trials, 2.3mL HCl were needed to titrate one serving of liquid antacid, 2.1mL of HCl were needed to titrate one serving of Rolaids, 1.6mL HCl were needed to titrate one serving of Tums, and 1.1mL HCl were needed to titrate one serving of Walgreens tablet.The true values, calculated using the amount of active bases in one serving of each product, affirmed Rolaids as the most basic, antacid liquid as the second most basic, and Tums and Walgreens tablet having the same lowest basicity.Even though the percent accuracy error for the experiment proved to be 98% for the Tums and antacid liquid, and 99% for the Rolaids and Walgreens tablet, the true order of basicity was close to the order deduced solely from the data.
TABLE SEVEN: ACID NEEDED TO TITRATE A FULL SERVING ACCORDING TO DATA GATHERED
Trial 1
Trial 2
Average
Tums Tablet
2.0mL/tablet
1.1mL/tablet
1.6mL/tablet
Rolaids Tablet
1.9mL/tablet
2.3mL/tablet
2.1mL/tablet
Walgreens Tablet
.63mL/tablet
1.6mL/tablet
1.1mL/tablet
Antacid Liquid
2.4mL/serving
2.2mL/serving
2.3mL/serving
TABLE EIGHT: ACTUAL ACID NEEDED TO TITRATE A FULL SERVING
HCl needed
Tums Tablet
100.mL
Rolaids Tablet
148mL
Walgreens Tablet
100.mL
Antacid Liquid
146mL
TABLE NINE: PERCENT ACCURACY ERROR BASED ON TABLE 8
% Accuracy Error
Tums Tablet
98%
Rolaids Tablet
99%
Walgreens Tablet
99%
Antacid Liquid
98%
*Calculations for tables 5-9: see lab notebook
JOURNAL ARTICLE: Yang YX, Lewis JD, Epstein S, Metz DC. 2006 December 27. Long-term proton pump
inhibitor therapy and risk of hip fracture. JAMA. 296(24): 2947-2953. http://jama.ama-assn.org/cgi/content/full/296/24/2947
LAB 14: THE EFFECTIVENESS OF ANTACIDS. Jacqueline. The purpose of the experiment was to determine the relative basicity of Tums, Rolaids, Walgreens Tablet and Walgreens Antacid Liquid. An acid base titration was used to determine the amount of HCl needed to titrate one serving of each antacid product. Using the average of two trials, 2.3mL HCl were needed to titrate one serving of liquid antacid, 2.1mL of HCl were needed to titrate one serving of Rolaids, 1.6mL HCl were needed to titrate one serving of Tums, and 1.1mL HCl were needed to titrate one serving of Walgreens tablet. The true values, calculated using the amount of active bases in one serving of each product, affirmed Rolaids as the most basic, antacid liquid as the second most basic, and Tums and Walgreens tablet having the same lowest basicity. Even though the percent accuracy error for the experiment proved to be 98% for the Tums and antacid liquid, and 99% for the Rolaids and Walgreens tablet, the true order of basicity was close to the order deduced solely from the data.
Key words: acid-base titration, double replacement reaction, solubility, antacids, pH
Results Tables:
JOURNAL ARTICLE:
Yang YX, Lewis JD, Epstein S, Metz DC. 2006 December 27. Long-term proton pump
inhibitor therapy and risk of hip fracture. JAMA. 296(24): 2947-2953.
http://jama.ama-assn.org/cgi/content/full/296/24/2947